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      Evidence based practice within biomedical scienceestablishes clear, systematic review methods to assess quality development of practiceeffectiveness. This in turn Improves healthcare quality and patient outcomes bydisseminating completed evidence reviews of practice effectiveness used toidentify evidence based laboratory medicine “best practices” as well this it Increasesengagement of laboratory professionals in quality improvement research and datacollection finally it Encourages recognition of laboratory professionals aspartners in healthcare policy and decision-making.  Evidence-based practice has done much toadvance healthcare, causing all methods of care to be based on the bestavailable credible evidence and to restrict the opinions of experts to be takenonly as opinions rather than proven facts. Section B – importance of EBP – PubMed Central (PMC) a full-text archiveof biomedical journal literature in association with the U.S.

NationalInstitutes of Health’s National Library of Medicine (NIH/NLM).9)     – Cochrane Database of Systematic Reviews. TheirLibrary offers an extensive collection of seven databases that contain diversetypes of high-quality, independent evidence to inform healthcaredecision-making, and information about Cochrane groups. Paper B – will individuals at riskof various forms of cardiovascular disease/problems have a definitive effect onmortality rates by the introduction of aspirin treatment.

 8)     Paper A – Can the long-term supplementationof aspirin with clopidogrel to an individual susceptible to cardiovasculardisorders such as coronary disease, peripheral arterial disease or ischemiccerebrovascular disease reduce the risk of events more than aspirin alone?   Paper C – measures use of aspirinamong populations, as well as if differences in gender exists in the use ofaspirin for secondary prevention among people with Coronary Heart Disease (CDH).Paper B – effectiveness of aspirinfor incidences of myocardial infarction (MI), stroke, all cardiovascular events(MI, stroke, and cardiovascular deaths), bleeding complications, and all-causemortality7)     Paper A – Risk of all cardiovascularevents were the outcome measures used to differentiate benefits and negativeeffects of adding clopidogrel to standard long-term aspirin therapy forpreventing cardiovascular events in people at elevated risk of cardiovasculardisease. 6)     Prevention  Paper C – A study of 1,869participants that were 40 years and greater who reported CHD or priormyocardial infarction.Paper B – A total of 48540 patients,25133 patients received aspirin and 23407 received placebo.5)     Paper A – A review of 28,165 people usingtwo separate trials using individuals experiencing acute coronary syndromes.

Clopidogrel was given along with antiplatelet treatment 4)     Paper B would be best for a busy practitioner.It is a condensed version and It reviews several primary studies but as asummary, producing the results needed in the shortest timeframe. Paper C – reviews data from thenationally representative 2000–2002 Medical Expenditure Panel Surveys.Paper B – Reviews of randomisedcontrolled trials from 1985 onward. (4 trials of meta-analysis in total)3)     Paper A – Paper A reviews data from tworandomised controlled trials.

 Paper C – primary study.Paper B – evidence- based journalabstract.2)     Paper A – systematic review. Paper C – example of a study.Paper B – a review of studies,articles and meta-analysis – synopses 1)     Paper A – Cochrane review, typically anexample of synthesis evidence EBP Case Study

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